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Xylitol
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Xylitol

Name of Product :Xylitol
Chemical Name : 1,2,3,4,5-Pentahydoxypentane
Molecular-Formula: C5H12O5
Molecular Weight: 152.15
Cas No.: [87-99-0]
 
Characteristics
Appearance: White crystalline or crystalline powder, it has a sweet taste odorless and a cooling.
Sensation : it water solution and transparent 1gdissolves in about 0.65ml of water.It is tiny to dissolve in the ether with Methyl alcohol, Melting Point: 92-96?, Boiling Point: 216?, 10% solution: PH5.0-7.0
 
Xylitol occurs naturally in many fruits and vegetables and is even produced by the human body during normal metabolism, produced commercially from plants such as corncob, birch and fibrous vegetation, xylitol has the same sweetness and bulk as sucrose with one-third calories (about 2.4 calories per Gram) and no unpleased aftertaste, It quickly dissolve and produces a cooling sensation in the mouth.
 
(1) Xylitol drug line---A Diabetic Fighter, Nutritional Agent and the Best Sweetener
 
Diabetes is known as the top third killer behind AIDS and cancer. It is therefore named "Sub-cancer" According to a survey conducted by the Chinese Academy of Preventive Medical Science, of over 40,000 permanent residents aged 20 to 74 across 11 provinces/municipalities, the morbidity ratio of diabetes was 3.21% and 4.76% has lower tolerance to sugar. That translates into 5000 to 6000 persons with either diabetic or lower tolerance to sugar. Out of which, 5% belongs to the former with most of the sufferers coming from children and young people and patients suffering acute attack and severe deficiency of insulin. The rest 95% belongs to the later with most of the sufferers from old people and patients of chronic symptoms and likely to be overlooked. Mere diabetes is not a serious problem. But its syndromes may be dangerous. For example, the acute syndromes may include ketonemia oxidosis, high permeability coma and lactic acidosis. The chronic
syndromes may cover cardiovascular, retina, renal and nervous pathologic process. Such syndromes not only afflict the patients but also endanger patient's life. For the sake of people's health, the Yucheng Futian Pharmacy Co., Ltd. and Shandong Provincial Institute of polyols Application joined hands and have developed an ideal drug for diabetics - Futian Xylitol
 
Character
Futain xylitol, namely pentose alcohol, is white crystal or crystal powder without odor. It tastes cool with the same saccharinity as that in cane sugar and the same calorific power as in glucose.
A cure applied in medical and health services
1. As a cure for diabetics, Futian Xylitol serves as an intermediate of sugar metabolism. By its unique way of metabolism, it produces 6-phosphofructose and phosphoglyceraldehyde directly via metabolism of pentose phosphate pathway without the necessity of promotion by insulin (it even promotes secretion of insulin). The 6-phosphofructose and phosphoglyceraldehyde thus produced can supply energy to the cells, maintain metabolic balance in body and effectively control diabetic syndromes. After use of this product, the commonly seen diabetic symptoms will be relieved gradually, and the users will be reported of reduced glycosuria. Through persistent use of this product, the symptoms will disappear.
2. As a cure for improving hepatic function, Futian Xylitol can slow down the producing process of fatty acid in plasma, but won`t cause higher blood sugar. After intake, the level of lactic acid, pyruvic acid and glucose in the blood will decrease, and insulin level will go up slightly. At the same time, the hepatic starch will increase while the aminotransferase will decrease. This is good for hepatitis B persisting type and cirrhosis. Obviously, it is an effective drug for hepatitis sufferers, especially for diabetics with accompanying hepatitis syndrome.
3. Bearing the effect of anti-ketone body, this product is an ideal anti-ketone drug for diabetics and starvation ketonemia.
 
Other medical effects of Futian Xylitol
1. It may be used as an infusion in surgical operation. It's clinically proved that Futian Xylitol has better blood stability than glucose, being an ideal sugar supplement used in internal and surgical treatment, especially after surgical anesthesia and surgical operation when there is something wrong with glucose metabolism and glucose can' t be utilized. Xylitol promotes the flow of red blood cells (RBC), maintains the negative charge of RBC, and controls the content of blood glutathione, thus shortening the healing process of surgical location.
2. It is effective in controlling formation of glycerol, neutral fat and free fatty acid, thus may be used to control weight gain and cure obesity.
3. Futian Xylitol has good heat stability. It will not generate chemical reaction when heated together with amino acid. Therefore, it may be mixed with amino acids and applied to various agents. Xylitol is also good for gastric secretion, pancreatic & biliary activity, adrenal cortex hormone, NADPH and ATP, suitable for aged and weak people.
4. As Futian Xylitol is absorbed by the intestinal wall at a pace slower than other sugars, it may be used in combination with laxative for senile constipation, and won' t cause pain and side effect.
 
Directions for use
To be infused in water before use, or to be taken with meal. For adults, 2 to 3 times daily with dosage of 20 to 40 g. For children, half of the dosage or follow doctor' s advice.
Cautions
1. In case of minor diarrhea with first time user or user taking this product at excessive dosage, reduce the dosage and the diarrhea will disappear. There is no other side effect.
2. Xylitol is likely to absorb moisture. Do not expose it to moisture when it' s stored
 

Insulin`s Effect in the Process of Sugar Metabolism and the Metabolic Pathway of Added-in Xylitol + Promotion – Inhibition

(2) Xylitol anticarious product line

The anticarious mechanism

utian Xylitol is resistant to the S mutant in mouth and won' t be fermented into harmful dental plaque acid. It inhibits the growth of dental plaque and acidic formation, stimulates the flow of protective saliva, changes the constituents of saliva, slows the reducing process of the pH value, and reduces the dental decay due to the plaque acid. Cane sugar also promotes saliva secretion, but that ' s not enough to overweigh the acidic effect caused by the streptococcal mutant. By contrast, after Futian Xylitol is taken, the basic amino acid and ammonia concentration in the saliva and at the carious plaque will rise, pushing up the pH value. As a result, the xylitol-5-phosphate will resettle on the enamel, thus re-strengthening the teeth and repairing impaired enamel. Futian Xylitol can inhibit bacterial reproduction and acid formation, thus leading to 90% reduction of acidic product by lactic acid bacteria and streptococcal mutant and resulting decrease of bacteria-dependent fatty phosphoric acid in the saliva and the plaques. As a result, the bacteria adsorbed to the dental surface are inhibited, and plaques are reduced in number.

Application and promotion of Futian Xylitol
Futain xylitol has an effect of inhibiting corrosion. Holding it in month from time to time will help prevent tooth caries. Due to this characteristic, it is widely used in gumdrop, chewing gum, candies and chocolate. In Japan, it`s also broadly applied in drugs and cosmetics.
Gumdrop made with xylitol as sweetener is designed for dental patients. In Europe, sugar-free chewing gum constitutes over 50% of the market. According to a German report, in 1997, the sugar-free type took a market share of 73% in the U.K., 71% in Germany, 57% in France, 53% in Italy, and 95% in Finland. As to other candies, in 1998, the sugar-free type constituted 47% in Switzerland, 25% in Germany, and 25% in Italy. Along with the developing economy and improving living standard, sugar-free foods are more and more popular with the mass Chinese consumers. Accordingly, they will take a growing market share year by year.

(3)Xylitol Foodstuff Line

According to a survey of 23 countries on death causes, the WHO called for giving up sugar. Excessive consumption of sugar is very likely to cause obesity, cardiovascular disease and diabetes, which, in turn, are major elements leading to shorter life span. Health foods are becoming a hit worldwide that is drawing more and more attention from consumers and developers. Function food made with xylitol instead of cane sugar has the advantages of good safety, taste, stability, and water-solubility, thus being more and more marketable.

With the advantages above, Futian Xylitol is used as the major ingredient of Futian Health Candy and Futian Teeth Healthy Candy.
I. About Futian Xylitol
Futain xylitol, namely pentose alcohol, is white crystal or crystal powder without odor. It tastes cool with the same saccharinity as that in cane sugar and the same calorific power with glucose.

II. Characters of Futian Xylitol
1. No browning reaction when heated.
When heated, cane sugar is likely to react with amino acid and turn brown. It ' s a major headache for most food processing. As xylitol doesn ' t have aldehyde group or ketone group in its structure and won ' t produce browning reaction when heated, it is therefore suitable for use in roasted foods with different tastes.
2. Resistant to yeast as a poor culture medium for microorganisms.
Due to this feature, it allows longer preservation time for food made with xylitol. For example, some customers prefer fruit jam with less sugar, but such fruit jam is more likely to become deteriorate after the container is opened. If xylitol is used instead of cane sugar, the fruit jam can be preserved for longer time without necessity to add any artificial preservative agent.


3. Moisture absorptive.
Futian Xylitol absorbs moisture, therefore, it ' s more suitable to soft cookies than cane sugar for lasting softness. For example, cake and bread made with xylitol tend to maintain softness for long time.
4. Cool feeling
Futian Xylitol has a capacity of heat solution as 10 times higher than that of cane sugar, in other words, when xylitol is dissolved, it tends to absorb large amount of heat, and makes the medium cooler. Food made with xylitol has a cool taste, augmenting the flavor of peppermint or spearmint.

( 4 )Xylitol Physical & Chemical Features

 

Sweetness Value

The sweetness value of xylitol equals that of sucrose, it is the highest compared with that of all other healthy alcohols.

 

Heat of Solution

Xylitol can absorb more quantity of heat than sorbitol in process of solution, it gives a pleasant cool and fresh sensation.

 

Acid Caused by Tartar

The bacteria in oral cavity will not utilize xylitol for fermentations. It does not yield acid and is anti-cariogenic.

 

Sweetness vs Temperature

Sweetness is higher at low temperature. The lower temperature the higher sweetness.

 

Solubility

Xylitol is a soluble sweetener. At an approximate human body temperature it is easier to be dissolved than sucrose.

 

Moisture Activeness

Lower than that of sorbitol. Facilitates the quality of preservation of foods.

 
Xylitol drug line | Xylitol anticarious product line | Other medical effects of Futian Xylitol | Directions for use

( 5 )Xylitol Packing

Packing: 1000 kg, 6 00kg, 25kg, 20kg , 500g, 250g, etc. Customer-required packages are also available.

( 6 )Xylitol Safety and Storage

Xylitol is slowly absorbed from the intestinal tract. Over-intake at one time may cause light diarrhea, however it depends on personal health conditions, the diarrhea will disappear a short time later when intake amounts return to normal.
Xylitol is hygroscopic. Please keep it in dry and ventilated place.

(7 )Specifications and Quality Standards

Identification \ Grade
FCC
USP
JP
BP
EP
E967
Assay                        %
98.5-101.0
98.5-101.0
 ≥98.0
98.0-102.0
  98.0-102.0
 ≥98.5
Other Polyols            %
 ≤2.0
 ≤2.0
                            ≤2.0(Related Products)
 
≤1.0
Loss on Drying          %
 ≤0.5
 ≤0.5
 ≤1.0
 ≤1.0
 ≤1.0
 ≤0.5
Residue on Ignition     %
 ≤0.5
 ≤0.5
 ≤0.1
 ≤0.1
 ≤0.1
Reducing Sugar        %
 ≤0.2
 ≤0.2
To pass test
 ≤0.2
 ≤0.2
≤0.2
Heavy Metal(as Pb)    %
 ≤0.0010
 ≤0.0010
 ≤0.00005
 ≤0.00005
 ≤0.0010
Nickel                        %
To pass test
 ≤0.0001
 ≤0.0001
 ≤0.0002
Lead                          %
 ≤0.0001
 ≤0.0005
 ≤0.0005
 ≤0.0001
Acidity or Alkalinity
To pass test
pH
5.0-7.0
5.0-7.0
Sulfates          %
 ≤0.006
 ≤0.02
Chloride                     %
 ≤0.005
 ≤0.01
Arsenic (as As2O3)   %
 ≤0.0003
 ≤0.00013
 ≤0.0003
Melting Range         ℃
92-96
93.0-95.0
92-96
92-96
92-96
Conductivity        us/cm
 ≤20
 ≤20
Identification Test
To pass test
To pass test
Pass A, B ,C
Pass A, B,C
Bacterial Endotoxins    I.U./g
≤2.5 (≥100g/L)
≤4.0 (≤100g/L)      

The grade required will depend very much on the final application.
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